Electrically Induced Limbic Seizures: Preliminary Findings in a Rodent Model
نویسندگان
چکیده
منابع مشابه
Electrically Induced Limbic Seizures: Preliminary Findings in a Rodent Model
In epilepsy, novel pharmacological and nonpharmacological treatment approaches are commonly assessed in model systems of acute motor and often generalized seizures. We developed a rodent model with short-term electrical stimulation of the perforant path resulting in stereotyped limbic seizures. Limbic structures play a major role in human intractable epilepsy. In 10 rats, single electrical 5-se...
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Normal human consciousness may be impaired by two possible routes: direct reduced function in widespread cortical regions or indirect disruption of subcortical activating systems. The route through which temporal lobe limbic seizures impair consciousness is not known. We recently developed an animal model that, like human limbic seizures, exhibits neocortical deactivation including cortical slo...
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ژورنال
عنوان ژورنال: Journal of Experimental Neuroscience
سال: 2015
ISSN: 1179-0695,1179-0695
DOI: 10.4137/jen.s23759